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Structure of 1858242-47-3
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This reagent enables efficient esterification under mild conditions, featuring a reactive dioxopyrrolidinyl leaving group paired with a propargyloxy-functionalized acetyl moiety. The alkyne handle facilitates downstream conjugation via click chemistry, while the bench-stable formulation ensures reliable performance in synthetic workflows.
2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate serves as a robust active ester for amide bond formation, enabling efficient coupling with amines under mild conditions. The propargylic ether moiety provides orthogonal reactivity and facilitates downstream transformations such as click chemistry. This reagent exhibits excellent bench stability, simplifies purification, and demonstrates broad functional group tolerance in peptide synthesis and conjugation workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: