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3-Amino-N,N-dimethylpropanamide

  • CAS No. 1857-18-7

  • Cat. No. CS-0051534
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Amino-N,N-dimethylpropanamide|CS-0051534

Structure of 1857-18-7

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General Information

  • CAS No. 1857-18-7
  • Cat. No. CS-0051534
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂N₂O
  • Molecular Weight 116.16
  • Synonym(s) 3-Amino-N,N-dimethyl-propionamide
  • SMILES CN(C)C(=O)CCN

Description

3-Amino-N,N-dimethylpropanamide features a primary amine group flanked by a dimethylamino carbonyl moiety, delivering enhanced solubility and stability under standard conditions. This polar, bench-stable compound integrates readily into peptide-like scaffolds and serves as a key intermediate in bioactive molecule synthesis.

Application

3-Amino-N,N-dimethylpropanamide serves as a versatile building block in medicinal chemistry, enabling the construction of diverse amide- and amine-containing scaffolds. Its primary amine functionality facilitates straightforward derivatization, while the N,N-dimethyl group enhances metabolic stability and lipophilicity. The compound exhibits good bench stability and is compatible with standard coupling protocols, simplifying purification and integration into multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.33
  • LogP   -0.5766
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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