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(1R)-1-Cyclobutylethan-1-amine hydrochloride

  • CAS No. 677743-79-2

  • Cat. No. CS-0055818
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1R)-1-Cyclobutylethan-1-amine hydrochloride|CS-0055818

Structure of 677743-79-2

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General Information

  • CAS No. 677743-79-2
  • Cat. No. CS-0055818
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClN
  • Molecular Weight 135.64
  • Synonym(s) (1R)-1-CYCLOBUTYLETHAN-1-AMINE HYDROCHLRIDE
  • SMILES C[C@H](C1CCC1)N.[H]Cl

Description

(1R)-1-Cyclobutylethan-1-amine hydrochloride is a chiral amine derivative featuring a cyclobutyl group attached to a stereodefined ethylamine backbone. This bench-stable, moisture-tolerant salt delivers a rigid, electron-rich scaffold for asymmetric synthesis and medicinal chemistry applications.

Application

(1R)-1-Cyclobutylethan-1-amine hydrochloride serves as a chiral building block for asymmetric synthesis, offering a rigid cyclobutyl moiety adjacent to a tunable amine function. The hydrochloride salt enhances bench stability and facilitates purification, while the stereogenic center enables enantioselective transformations. It functions effectively in nucleophilic substitutions, reductive aminations, and as a scaffold for bioactive heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.5555
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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