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Structure of 185332-92-7
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Sulfo-GMBS is a water-soluble, maleimide-functional crosslinker designed for bioconjugation under physiological conditions. This reagent features a sulfonate group that enhances solubility in aqueous buffers while maintaining high reactivity with thiol-containing biomolecules. The maleimide moiety enables efficient, site-specific coupling to cysteine residues in proteins and peptides. Ideal for antibody-drug conjugates and protein labeling workflows.
Sulfo-GMBS serves as a water-soluble, amine-reactive crosslinker for bioconjugation applications. Its sulfhydryl-reactive maleimide group enables site-specific labeling of thiol-containing biomolecules, while the charged sulfonate moiety enhances solubility in aqueous buffers. The reagent facilitates efficient conjugation under physiological conditions and is well-suited for protein-protein, protein-oligonucleotide, and antibody-drug conjugation workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: