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CS-W001157 4
Total: USD 88.00

3-Hydroxypyridine-4-carboxaldehyde

  • CAS No. 1849-54-3

  • Cat. No. CS-W005203
  • Purity≥98%
  • MDL No.MFCD01318565

*For research and further manufacturing use only, not for direct human use.

3-Hydroxypyridine-4-carboxaldehyde|CS-W005203

Structure of 1849-54-3

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General Information

  • CAS No. 1849-54-3
  • Cat. No. CS-W005203
  • Purity ≥98%
  • MDL No. MFCD01318565
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅NO₂
  • Molecular Weight 123.11
  • Synonym(s) 4-Formyl-3-hydroxypyridine 3-Hydroxy-isonicotinaldehyde
  • SMILES C1=C(C(=CN=C1)O)C=O

Description

3-Hydroxypyridine-4-carboxaldehyde features a strategically positioned aldehyde group flanked by a hydroxyl and a pyridine nitrogen, enabling versatile conjugation in synthetic applications. This scaffold integrates readily into bioactive molecule frameworks due to its polar yet planar architecture and enhanced solubility under standard conditions.

Application

3-Hydroxypyridine-4-carboxaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through its dual functionality. The aldehyde group facilitates nucleophilic additions and condensation reactions, while the phenolic hydroxyl supports derivatization and metal coordination. Its stability under standard bench conditions and compatibility with common protecting groups enhance utility in multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   0.5997
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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