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CS-W001157 4
Total: USD 88.00

2-(2-Methoxyphenoxy)ethylamine

  • CAS No. 1836-62-0

  • Cat. No. CS-W002568
  • Purity≥98%
  • MDL No.MFCD00235185

*For research and further manufacturing use only, not for direct human use.

2-(2-Methoxyphenoxy)ethylamine|CS-W002568

Structure of 1836-62-0

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General Information

  • CAS No. 1836-62-0
  • Cat. No. CS-W002568
  • Purity ≥98%
  • MDL No. MFCD00235185
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO₂
  • Molecular Weight 167.21
  • Synonym(s) o-Methoxy Phenoxy Ethamine; 2-(2-Methoxyphenoxy)ethylamine
  • SMILES COC1=CC=CC=C1OCCN

Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Application

2-(2-Methoxyphenoxy)ethylamine serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient synthesis of bioactive heterocycles and peptide conjugates. The primary amine facilitates coupling reactions, while the ortho-methoxyphenyl ether moiety provides structural rigidity and metabolic stability. This compound exhibits good bench stability and is compatible with standard protection/deprotection sequences, making it suitable for iterative synthetic workflows in API development.

Synthesis

  • Route1
    • null|null
      214778-48-0
    • ~90%
    • In-stock
      2-(2-Methoxyphenoxy)ethylamine|CS-W002568
      1836-62-0

    References

    • Alanine, Alexander; Gobbi, Luca Claudio; Kolczewski, Sabine; Luebbers, Thomas; Peters, Jens-Uwe; Steward, Lucinda Patent: US2006/252779 A1, 2006 ; Location in patent: Page/Page column 7 ; US 20060252779 A1
  • Route2
    • 2-(2-(2-Methoxyphenoxy)ethyl)isoindoline-1,3-dione|CS-0349215
      26646-63-9
    • ~85%
    • In-stock
      2-(2-Methoxyphenoxy)ethylamine|CS-W002568
      1836-62-0

    References

    • Carocci, Alessia; Catalano, Alessia; Lovece, Angelo; Lentini, Giovanni; Duranti, Andrea; Lucini, Valeria; Pannacci, Marilou; Scaglione, Francesco; Franchini, Carlo Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 17 p. 6496 - 6511
  • Route3

    References

    • Valhondo, Margarita; Marco, Isabel; Martin-Fontecha, Mar; Vazquez-Villa, Henar; Ramos, Jose A.; Berkels, Reinhard; Lauterbach, Thomas; Benhamu, Bellinda; Lopez-Rodriguez, Maria L. Journal of Medicinal Chemistry, 2013 , vol. 56, # 20 p. 7851 - 7861

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.0327
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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