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2-(2-Methoxyphenoxy)ethylamine Carvedilol Impurity

  • CAS No. 1836-62-0

  • Cat. No. CS-0229054
  • Molecule weight167.21
  • Purity≥98%
  • MDL No.MFCD00235185

*For research and further manufacturing use only, not for direct human use.

2-(2-Methoxyphenoxy)ethylamine Carvedilol Impurity|CS-0229054

Structure of 1836-62-0

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General Information

  • CAS No. 1836-62-0
  • Cat. No. CS-0229054
  • Purity ≥98%
  • MDL No. MFCD00235185
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO₂
  • Molecular Weight 167.21
  • Synonym(s) o-Methoxy Phenoxy Ethamine
  • SMILES COC1=CC=CC=C1OCCN

Synthesis

  • Route1
    • null|null
      214778-48-0
    • ~90%
    • 2-(2-Methoxyphenoxy)ethylamine Carvedilol Impurity|CS-0229054
      1836-62-0

    References

    • Alanine, Alexander; Gobbi, Luca Claudio; Kolczewski, Sabine; Luebbers, Thomas; Peters, Jens-Uwe; Steward, Lucinda Patent: US2006/252779 A1, 2006 ; Location in patent: Page/Page column 7 ; US 20060252779 A1
  • Route2
    • 2-(2-(2-Methoxyphenoxy)ethyl)isoindoline-1,3-dione|CS-0349215
      26646-63-9
    • ~85%
    • 2-(2-Methoxyphenoxy)ethylamine Carvedilol Impurity|CS-0229054
      1836-62-0

    References

    • Carocci, Alessia; Catalano, Alessia; Lovece, Angelo; Lentini, Giovanni; Duranti, Andrea; Lucini, Valeria; Pannacci, Marilou; Scaglione, Francesco; Franchini, Carlo Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 17 p. 6496 - 6511
  • Route3

    References

    • Valhondo, Margarita; Marco, Isabel; Martin-Fontecha, Mar; Vazquez-Villa, Henar; Ramos, Jose A.; Berkels, Reinhard; Lauterbach, Thomas; Benhamu, Bellinda; Lopez-Rodriguez, Maria L. Journal of Medicinal Chemistry, 2013 , vol. 56, # 20 p. 7851 - 7861

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.0327
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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