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Structure of 1824276-00-7
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3-(Trifluoromethyl)quinolin-7-amine features a trifluoromethyl group at the 3-position and an amine handle at the 7-position of the quinoline scaffold. This electron-deficient heteroaromatic system integrates readily into medicinal chemistry campaigns, offering enhanced metabolic stability and improved membrane permeability in bioactive molecule design.
3-(Trifluoromethyl)quinolin-7-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through palladium-catalyzed coupling reactions. Its trifluoromethyl group enhances metabolic stability and membrane permeability, while the quinolin-7-amine scaffold provides a rigid, planar framework for target engagement. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating efficient functionalization and purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: