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Structure of 1080640-91-0
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8-(Trifluoromethyl)quinolin-6-amine features a trifluoromethyl group at the 8-position of a quinoline scaffold, enhancing electron-withdrawing character and metabolic stability. This nitrogen-rich heterocycle integrates readily into pharmaceutical scaffolds, offering improved solubility and target engagement in kinase inhibitor design.
8-(Trifluoromethyl)quinolin-6-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles. Its trifluoromethyl group enhances metabolic stability and membrane permeability, while the amine functionality facilitates direct coupling reactions or derivatization. The molecule exhibits excellent bench stability and compatibility with standard synthetic protocols, making it well-suited for parallel synthesis campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: