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CS-W001157 4
Total: USD 88.00

7-Fluoroindoline hydrochloride

  • CAS No. 1820711-83-8

  • Cat. No. CS-0160499
  • Purity≥98%
  • MDL No.MFCD27923560

*For research and further manufacturing use only, not for direct human use.

7-Fluoroindoline hydrochloride|CS-0160499

Structure of 1820711-83-8

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General Information

  • CAS No. 1820711-83-8
  • Cat. No. CS-0160499
  • Purity ≥98%
  • MDL No. MFCD27923560
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉ClFN
  • Molecular Weight 173.62
  • Synonym(s) None
  • SMILES FC1=CC=CC2=C1NCC2.[H]Cl

Description

7-Fluoroindoline hydrochloride offers a fluorinated indoline scaffold with enhanced solubility and stability under standard conditions. The electron-deficient aromatic ring facilitates coupling reactions, while the protonated amine enables salt formation for improved handling. This building block integrates efficiently into medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.

Application

7-Fluoroindoline hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated indoline scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. Its bench-stable nature and compatibility with standard coupling and functionalization protocols facilitate straightforward incorporation into diverse molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   2.2155
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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