Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-4-iodo-1-methoxybenzene

  • CAS No. 182056-39-9

  • Cat. No. CS-0097745
  • Purity≥97%
  • MDL No.MFCD03425935

*For research and further manufacturing use only, not for direct human use.

2-Bromo-4-iodo-1-methoxybenzene|CS-0097745

Structure of 182056-39-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 182056-39-9
  • Cat. No. CS-0097745
  • Purity ≥97%
  • MDL No. MFCD03425935
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrIO
  • Molecular Weight 312.93
  • Synonym(s) 2-Bromo-4-iodophenyl methyl ether
  • SMILES COC1=CC=C(I)C=C1Br

Description

2-Bromo-4-iodo-1-methoxybenzene features a strategically positioned methoxy group that enhances solubility and directs electrophilic substitution, while the bromo and iodo substituents enable sequential cross-coupling reactions. This ortho-disubstituted aromatic scaffold serves as a high-precision intermediate for constructing complex biaryl architectures in medicinal chemistry and materials science.

Application

2-Bromo-4-iodo-1-methoxybenzene serves as a versatile dihalogenated aromatic building block for palladium-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization via Suzuki, Stille, or Negishi couplings, while the methoxy group provides electronic modulation and orthogonal reactivity. Its bench-stable crystalline form facilitates handling and purification, making it ideal for constructing complex scaffolds in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • Yusubov, Mekhman S.; Tveryakova, Elena N.; Krasnokutskaya, Elena A.; Perederyna, Irina A.; Zhdankin, Viktor V. Synthetic Communications, 2007 , vol. 37, # 8 p. 1259 - 1265
  • Route2

    References

    • Conway, Ben; Crosbie, Elaine; Kennedy, Alan R.; Mulvey, Robert E.; Robertson, Stuart D. Chemical Communications, 2012 , vol. 48, # 39 p. 4674 - 4676
  • Route3
    • null|null
      540-38-5
    • ~%
    • In-stock
      2-Bromo-4-iodo-1-methoxybenzene|CS-0097745
      182056-39-9

    References

    • Heinrich, Annika C. J.; Thiedemann, Birk; Gates, Paul J.; Staubitz, Anne Organic Letters, 2013 , vol. 15, # 18 p. 4666 - 4669

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   9.23
  • LogP   3.0623
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromo-4-iodo-1-methoxybenzene sigma2-Bromo-4-iodo-1-methoxybenzene manufacturer2-Bromo-4-iodo-1-methoxybenzene price2-Bromo-4-iodo-1-methoxybenzene structure2-Bromo-4-iodo-1-methoxybenzene SDSbuy 2-Bromo-4-iodo-1-methoxybenzene2-Bromo-4-iodo-1-methoxybenzene supplier2-Bromo-4-iodo-1-methoxybenzene uses2-Bromo-4-iodo-1-methoxybenzene molecular weightprice of 2-Bromo-4-iodo-1-methoxybenzene2-Bromo-4-iodo-1-methoxybenzene chemical name formula of 2-Bromo-4-iodo-1-methoxybenzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label