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Structure of 1818847-43-6
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1-Methylazetidin-3-one hydrochloride is a bench-stable, moisture-tolerant heterocyclic amide featuring a strained four-membered ring system. This compact scaffold integrates readily into medicinal chemistry libraries, delivering enhanced metabolic stability and improved solubility in polar solvents. Its electron-deficient carbonyl group facilitates nucleophilic addition reactions under mild conditions.
1-Methylazetidin-3-one hydrochloride serves as a stable, bench-ready building block for medicinal chemistry and process development. Its strained four-membered lactam ring enables efficient functionalization at the C3 position and facilitates coupling reactions with nucleophiles under mild conditions. The N-methyl group enhances metabolic stability and modulates solubility, while the hydrochloride salt improves crystallinity and handling. Widely used in the synthesis of bioactive heterocycles, it functions as a key intermediate in constructing azetidine-based scaffolds found in pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: