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CS-W001157 4
Total: USD 88.00

(Iodoethynyl)trimethylsilane

  • CAS No. 18163-47-8

  • Cat. No. CS-W013073
  • Purity≥97%
  • MDL No.MFCD00274201

*For research and further manufacturing use only, not for direct human use.

(Iodoethynyl)trimethylsilane|CS-W013073

Structure of 18163-47-8

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General Information

  • CAS No. 18163-47-8
  • Cat. No. CS-W013073
  • Purity ≥97%
  • MDL No. MFCD00274201
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉ISi
  • Molecular Weight 224.12
  • Synonym(s) 1-Iodo-2-(trimethylsilyl)acetylene
  • SMILES C[Si](C#CI)(C)C

Description

1-Iodo-2-(trimethylsilyl)acetylene may be used to investigate the reactivity of diamagnetic cobalt(I) complex, Tol-BDI((2-pp)2)Co [Tol-BDI((2-pp)2)H = 2-(4-tolyl)-1,3-bis(2-isopropylpyridyl)propenediimine]. It may be used for the synthesis of 1-(4-trimethylsilanylbuta-1,3-diynyl)pyrene, via Pd-coupling with 1-iodo-2-trimethylsilylacetylene.

Application

(Iodoethynyl)trimethylsilane serves as a reliable, bench-stable building block for Sonogashira coupling reactions and alkyne functionalization. Its terminal alkyne moiety enables efficient C–C bond formation under mild palladium catalysis, while the trimethylsilyl group provides enhanced stability and facilitates selective deprotection. This reagent functions effectively in diverse synthetic contexts, including heterocycle construction and late-stage functionalization, offering predictable reactivity and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07,GHS08
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302+H312+H332-H317-H334-H361
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P272-P280-P304+P340-P330-P363-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.2597
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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