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CS-W001157 4
Total: USD 88.00

2-Fluoro-6-iodoaniline

  • CAS No. 886762-73-8

  • Cat. No. CS-0001998
  • Purity≥97%
  • MDL No.MFCD07368681

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-6-iodoaniline|CS-0001998

Structure of 886762-73-8

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General Information

  • CAS No. 886762-73-8
  • Cat. No. CS-0001998
  • Purity ≥97%
  • MDL No. MFCD07368681
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅FIN
  • Molecular Weight 237.01
  • Synonym(s) benzenamine, 2-fluoro-6-iodo-
  • SMILES NC(C(I)=CC=C1)=C1F

Description

2-Fluoro-6-iodoaniline features a strategically positioned fluorine and iodine substituent on the aromatic ring, enabling selective cross-coupling reactions. This electron-deficient aniline derivative integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity under standard conditions.

Application

2-Fluoro-6-iodoaniline serves as a versatile building block for Suzuki-Miyaura and Ullmann-type coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-fluoro and iodo substituents provide complementary reactivity for sequential functionalization, while the aniline moiety offers good bench stability and ease of purification. Its defined regiochemistry facilitates predictable transformation in medicinal chemistry and materials synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.0125
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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