Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Quinolinol, 8-chloro-

  • CAS No. 18119-24-9

  • Cat. No. CS-0029519
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Quinolinol, 8-chloro-|CS-0029519

Structure of 18119-24-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 18119-24-9
  • Cat. No. CS-0029519
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆ClNO
  • Molecular Weight 179.60
  • Synonym(s) 8-Chloro-6-hydroxyquinoline
  • SMILES OC1=CC(Cl)=C2N=CC=CC2=C1

Description

8-Chloroquinolin-6-ol delivers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry and materials synthesis. This bench-stable compound features a strategically positioned chloro group and phenolic hydroxyl, enabling direct functionalization or metal coordination. The dual functionality supports modular derivatization in catalyst design and bioactive molecule development.

Application

8-Chloroquinolin-6-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of quinoline-based scaffolds. Its ortho-chloro and phenolic hydroxyl groups facilitate subsequent cross-coupling reactions and derivatization under standard conditions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis workflows in API development.

Synthesis

  • Route1

    References

    • Wyeth Patent: US2007/27160 A1, 2007 ; Location in patent: Page/Page column 43 ; US 20070027160 A1
  • Route2

    References

    • WYETH Patent: WO2004/99191 A2, 2004 ; Location in patent: Page 33 ; WO 2004/099191 A2
  • Route3
    • In-stock
      4-Amino-3-chlorophenol hydrochloride|CS-W017237
      52671-64-4
    • null|null
      98-95-3
    • ~77%
    • In-stock
      6-Quinolinol, 8-chloro-|CS-0029519
      18119-24-9

    References

    • WYETH Patent: WO2007/146116 A2, 2007 ; Location in patent: Page/Page column 28 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.5938
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Quinolinol, 8-chloro- sigma6-Quinolinol, 8-chloro- manufacturer6-Quinolinol, 8-chloro- price6-Quinolinol, 8-chloro- structure6-Quinolinol, 8-chloro- SDSbuy 6-Quinolinol, 8-chloro-6-Quinolinol, 8-chloro- supplier6-Quinolinol, 8-chloro- uses6-Quinolinol, 8-chloro- molecular weightprice of 6-Quinolinol, 8-chloro-6-Quinolinol, 8-chloro- chemical name formula of 6-Quinolinol, 8-chloro-
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label