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CS-W001157 4
Total: USD 88.00

2,5-Dimethoxyphenol

  • CAS No. 18113-18-3

  • Cat. No. CS-W023061
  • Purity≥98%
  • MDL No.MFCD00094237

*For research and further manufacturing use only, not for direct human use.

2,5-Dimethoxyphenol|CS-W023061

Structure of 18113-18-3

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General Information

  • CAS No. 18113-18-3
  • Cat. No. CS-W023061
  • Purity ≥98%
  • MDL No. MFCD00094237
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O₃
  • Molecular Weight 154.17
  • Synonym(s) Phenol, 2,5-diMethoxy-
  • SMILES COC1=CC=C(OC)C(O)=C1

Application

2,5-Dimethoxyphenol serves as a valuable building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and natural product analogs. Its ortho-dimethoxy substitution pattern confers enhanced stability and facilitates selective functionalization in electrophilic aromatic substitution reactions. The compound functions effectively in coupling processes and acts as a key intermediate in the synthesis of pharmaceutical scaffolds and agrochemical derivatives, offering predictable reactivity and straightforward purification.

Synthesis

  • Route1

    References

    • Tetrahedron Letters, , vol. 46, # 50 p. 8665 - 8668
  • Route2
    • 2,5-Dimethoxyphenyl acetate|CS-0661533
      27257-06-3
    • ~98%
    • In-stock
      2,5-Dimethoxyphenol|CS-W023061
      18113-18-3

    References

    • European Journal of Organic Chemistry, , # 16 p. 3132 - 3141
  • Route3
    • null|null
      84019-67-0
    • ~81%
    • In-stock
      2,5-Dimethoxyphenol|CS-W023061
      18113-18-3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 11 p. 2979 - 2988

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H311-H315-H318-H332-H402
Precautionary Statements : P261-P264-P270-P271-P273-P280-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.69
  • LogP   1.4094
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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