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Hydroxy-PEG5-C1-Boc

  • CAS No. 1807530-05-7

  • Cat. No. CS-0114869
  • Purity≥97%
  • MDL No.MFCD27977509

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG5-C1-Boc|CS-0114869

Structure of 1807530-05-7

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General Information

  • CAS No. 1807530-05-7
  • Cat. No. CS-0114869
  • Purity ≥97%
  • MDL No. MFCD27977509
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₂O₈
  • Molecular Weight 352.42
  • Synonym(s) Hydroxy-PEG5-t-butyl acetate
  • SMILES O=C(OC(C)(C)C)COCCOCCOCCOCCOCCO

Description

Hydroxy-PEG5-C1-Boc features a hydroxyl-terminated PEG5 chain linked to a C1 spacer and protected with a Boc group. This bifunctional scaffold enables selective conjugation and controlled deprotection, ideal for bioconjugation workflows requiring orthogonal handling. The PEG5 segment imparts solubility and stability under standard conditions.

Application

Hydroxy-PEG5-C1-Boc serves as a versatile, bench-stable linker for conjugation and protection strategies in peptide and oligonucleotide synthesis. The PEG5 spacer provides enhanced solubility and reduced aggregation, while the Boc group enables mild deprotection under acidic conditions. The terminal hydroxyl facilitates further functionalization via esterification or ether formation, making it ideal for modular assembly of bioconjugates and prodrug architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   92.68
  • LogP   0.4034
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   16

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