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CS-W001157 4
Total: USD 88.00

4-(Trifluoromethyl)benzenepropanol Cinacalcet Impurity

  • CAS No. 180635-74-9

  • Cat. No. CS-0229378
  • Purity≥98%
  • MDL No.MFCD09028744

*For research and further manufacturing use only, not for direct human use.

4-(Trifluoromethyl)benzenepropanol Cinacalcet Impurity|CS-0229378

Structure of 180635-74-9

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General Information

  • CAS No. 180635-74-9
  • Cat. No. CS-0229378
  • Purity ≥98%
  • MDL No. MFCD09028744
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁F₃O
  • Molecular Weight 204.19
  • Synonym(s) 3-(4-(Trifluoromethyl)phenyl)propan-1-ol
  • SMILES FC(F)(F)C1=CC=C(CCCO)C=C1

Synthesis

  • Route1
    • 3-(4-(Trifluoromethyl)phenyl)propanoic acid Cinacalcet Impurity|CS-0213955
      53473-36-2
    • ~99%
    • 4-(Trifluoromethyl)benzenepropanol Cinacalcet Impurity|CS-0229378
      180635-74-9

    References

    • ACTELION PHARMACEUTICALS LTD Patent: WO2008/78291 A1, 2008 ; Location in patent: Page/Page column 47 ; WO 2008/078291 A1
  • Route2

    References

    • Hamilton, Gregory S.; Wu, Yong-Qian; Limburg, David C.; Wilkinson, Douglas E.; Vaal, Mark J.; Li, Jia-He; Thomas, Christine; Huang, Wei; Sauer, Hansjorg; Ross, Douglas T.; Soni, Raj; Chen, Yi; Guo, Hongshi; Howorth, Pamela; Valentine, Heather; Liang, Shi; Spicer, Dawn; Fuller, Mike; Steiner, Joseph P. Journal of Medicinal Chemistry, 2002 , vol. 45, # 16 p. 3549 - 3557
  • Route3

    References

    • Hamilton, Gregory S.; Wu, Yong-Qian; Limburg, David C.; Wilkinson, Douglas E.; Vaal, Mark J.; Li, Jia-He; Thomas, Christine; Huang, Wei; Sauer, Hansjorg; Ross, Douglas T.; Soni, Raj; Chen, Yi; Guo, Hongshi; Howorth, Pamela; Valentine, Heather; Liang, Shi; Spicer, Dawn; Fuller, Mike; Steiner, Joseph P. Journal of Medicinal Chemistry, 2002 , vol. 45, # 16 p. 3549 - 3557

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.6303
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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