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Structure of 180605-36-1
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2-(4-Methyl-1-piperazinyl)aniline features a piperazine ring fused to an aromatic amine, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in pharmaceutical intermediates and kinase inhibitor development.
2-(4-Methyl-1-piperazinyl)aniline serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and drug candidates. Its aniline functionality facilitates Suzuki and Buchwald–Hartwig couplings, while the piperazine ring offers tunable basicity and solubility. The methylated piperazine enhances metabolic stability and functional group tolerance, supporting efficient synthesis and purification in multi-step campaigns.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3263
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: