Cl-C6-PEG4-O-CH2COOH

Name: Cl-C6-PEG4-O-CH2COOH
Brand: ChemScene
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CAS No. 1799506-30-1
Cat. No. CS-0046142
Purity≥98%
MDL No.MFCD31692394

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 1799506-30-1

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General Information

CAS No. 1799506-30-1
Cat. No. CS-0046142
Purity ≥98%
MDL No. MFCD31692394
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₃₁ClO₇
Molecular Weight 370.87
Synonym(s) PROTAC Linker 4
SMILES ClCCCCCCOCCOCCOCCOCCOCC(O)=O

Description

Cl-C6-PEG4-O-CH2COOH features a chlorinated phenyl group linked via a four-ethylene glycol chain to a carboxylic acid terminus. This bifunctional construct combines halogen-directed coupling potential with hydrophilic PEG spacing and a reactive carboxyl handle for bioconjugation or surface immobilization under standard conditions.

Application

Cl-C₆-PEG₄-O-CH₂COOH serves as a versatile bifunctional linker for conjugation and solid-phase synthesis. The chloroaryl group enables efficient coupling with nucleophilic amines, while the terminal carboxylic acid facilitates amide bond formation. Its PEG4 spacer provides solubility and reduces aggregation, enhancing performance in bioconjugation and peptide chemistry workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 83.45
LogP 1.9532
H_Acceptors 6
H_Donors 1
Rotatable_Bonds 20

Other Classifications

Life Science Linker Bromo PEG

Life Science Linker PEG Acid

Building Blocks Skeleton Fatty chain compounds

Building Blocks Functional Group PEG

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation Functionality Creating Reagents

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Chemical Biology Pharmaceutical Development and Drug Discovery Research Bioconjugation Functionality Creating Reagents

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Cl-C6-PEG4-O-CH2COOH

CAS No. 1799506-30-1

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