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CS-W001157 4
Total: USD 88.00

2-(2-((6-Chlorohexyl)oxy)ethoxy)acetic acid

  • CAS No. 2231744-57-1

  • Cat. No. CS-0046340
  • Purity≥95%
  • MDL No.MFCD31706239

*For research and further manufacturing use only, not for direct human use.

2-(2-((6-Chlorohexyl)oxy)ethoxy)acetic acid|CS-0046340

Structure of 2231744-57-1

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General Information

  • CAS No. 2231744-57-1
  • Cat. No. CS-0046340
  • Purity ≥95%
  • MDL No. MFCD31706239
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉ClO₄
  • Molecular Weight 238.71
  • Synonym(s) None
  • SMILES ClCCCCCCOCCOCC(O)=O

Description

This bifunctional linker features a hydrophilic polyether chain terminating in a carboxylic acid, enabling conjugation to biomolecules or solid supports. The chlorine-bearing hexyl spacer enhances lipophilicity and provides a handle for further functionalization, while the ether linkages ensure stability under basic conditions.

Application

2-(2-((6-Chlorohexyl)oxy)ethoxy)acetic acid serves as a versatile bifunctional building block, enabling the introduction of both hydrophilic ether linkages and reactive carboxylic acid handles in synthetic sequences. Its pendant chloroalkyl chain facilitates downstream functionalization via nucleophilic substitution, while the terminal carboxylic acid supports amide coupling or esterification. The molecule exhibits good bench stability and is compatible with standard purification methods, making it suitable for modular synthesis of complex architectures in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   1.9034
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   11

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