6-Amino-1-methylpyridin-2(1h)-one

Name: 6-Amino-1-methylpyridin-2(1h)-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 17920-37-5
Cat. No. CS-0780218
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

6-Amino-1-methylpyridin-2(1h)-one|CS-0780218

Structure of 17920-37-5

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Description

6-Amino-1-methylpyridin-2(1H)-one features a pyridinone core with a methyl group at C1 and an amino substituent at C6, delivering enhanced solubility and stability. This electron-rich scaffold integrates readily into heterocyclic synthesis, serving as a key building block for bioactive molecules in medicinal chemistry and materials science.

Application

6-Amino-1-methylpyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridone-based scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. The amino group facilitates direct functionalization, while the 1-methyl substitution enhances metabolic stability and modulates solubility. This compound exhibits bench stability and compatibility with standard coupling reactions, simplifying purification and integration into multi-step syntheses.

General Information

CAS No. 17920-37-5
Cat. No. CS-0780218
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₈N₂O
Molecular Weight 124.14
Synonym(s) None
SMILES CN1C(C=CC=C1N)=O

Computational Chemistry Data

TPSA 48.02
LogP -0.0325
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Amino-1-methylpyridin-2(1h)-one

CAS No. 17920-37-5

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