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tert-Butyl piperidin-4-ylcarbamate hydrochloride

  • CAS No. 179110-74-8

  • Cat. No. CS-0041692
  • Purity≥95%
  • MDL No.MFCD03093509

*For research and further manufacturing use only, not for direct human use.

tert-Butyl piperidin-4-ylcarbamate hydrochloride|CS-0041692

Structure of 179110-74-8

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General Information

  • CAS No. 179110-74-8
  • Cat. No. CS-0041692
  • Purity ≥95%
  • MDL No. MFCD03093509
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁ClN₂O₂
  • Molecular Weight 236.74
  • Synonym(s) tert-butyl 4-amino-1-piperidinecarboxylate hydrochloride
  • SMILES O=C(OC(C)(C)C)NC1CCNCC1.[H]Cl

Description

This bench-stable carbamate derivative features a tert-butyl-protected piperidin-4-yl moiety, enabling efficient incorporation into complex amine scaffolds. The hydrochloride salt enhances solubility and stability during synthetic workflows, facilitating seamless integration in medicinal chemistry campaigns targeting bioactive heterocycles.

Application

tert-Butyl piperidin-4-ylcarbamate hydrochloride serves as a robust, bench-stable building block for medicinal chemistry and process synthesis. The protected piperidine scaffold enables efficient late-stage functionalization, while the tert-butyl carbamate group offers orthogonal deprotection under mild acidic conditions. Its high functional group tolerance facilitates incorporation into diverse heterocyclic frameworks and API intermediates, particularly in kinase inhibitor and CNS-targeted compound development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.6849
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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