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CS-W001157 4
Total: USD 88.00

2-BROMOTHIENO[3,2-C]PYRIDIN-4-AMINE

  • CAS No. 1784280-46-1

  • Cat. No. CS-W000638
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-BROMOTHIENO[3,2-C]PYRIDIN-4-AMINE|CS-W000638

Structure of 1784280-46-1

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General Information

  • CAS No. 1784280-46-1
  • Cat. No. CS-W000638
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂S
  • Molecular Weight 229.10
  • Synonym(s) None
  • SMILES Brc1sc2c(c1)c(N)ncc2

Description

2-Bromothieno[3,2-c]pyridin-4-amine features a fused thienopyridine core with a bromine atom at the 2-position and an amine group at the 4-position. This scaffold delivers a rigid, electron-deficient heterocycle ideal for coupling reactions in medicinal chemistry. The bromine serves as a versatile handle for palladium-catalyzed transformations, while the amine enables direct derivatization or salt formation. Bench-stable under standard conditions, it integrates efficiently into diverse molecular architectures.

Application

2-Bromothieno[3,2-c]pyridin-4-amine serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent and electron-rich nitrogen framework. The molecule exhibits bench stability, facilitates straightforward purification, and functions effectively in the construction of complex scaffolds relevant to medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.641
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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