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CS-W001157 4
Total: USD 88.00

3-Chloro-2,2-bis(chloromethyl)propanoic acid

  • CAS No. 17831-70-8

  • Cat. No. CS-W021894
  • Purity≥98%
  • MDL No.MFCD00021685
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Chloro-2,2-bis(chloromethyl)propanoic acid|CS-W021894

Structure of 17831-70-8

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Description

This chlorinated carboxylic acid features a sterically hindered core with two geminal chloromethyl groups, enhancing its reactivity in electrophilic transformations. The electron-withdrawing chlorine atoms stabilize adjacent intermediates, enabling efficient coupling reactions under mild conditions. Its bench-stable nature supports reliable handling in synthetic workflows.

Application

3-Chloro-2,2-bis(chloromethyl)propanoic acid serves as a versatile synthetic building block for constructing densely functionalized carbon frameworks. Its trifunctional architecture—combining a carboxylic acid with two geminal chloromethyl groups—enables sequential derivatization via nucleophilic substitution, enabling rapid access to complex heterocycles and side-chain-modified scaffolds. The molecule exhibits bench stability under standard anhydrous conditions and facilitates clean transformations in established coupling protocols, making it suitable for modular synthesis workflows in medicinal chemistry and process development.

General Information

  • CAS No. 17831-70-8
  • Cat. No. CS-W021894
  • Purity ≥98%
  • MDL No. MFCD00021685
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇Cl₃O₂
  • Molecular Weight 205.47
  • Synonym(s) TRIS(CHLOROMETHYL)ACETIC ACID
  • SMILES O=C(O)C(CCl)(CCl)CCl

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.7738
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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