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Structure of 13511-38-1
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This sterically hindered acylating agent features a chlorine-substituted, gem-dimethylated carbon backbone, enabling efficient coupling reactions under mild conditions. The electron-withdrawing chloride enhances carbonyl electrophilicity while the bulky tert-butyl-like structure minimizes side reactions. Ideal for peptide synthesis and functionalization workflows requiring high selectivity and stability.
3-Chloro-2,2-dimethylpropanoic acid serves as a versatile building block in synthetic organic chemistry, enabling the efficient construction of sterically hindered carboxylic acid derivatives. Its α-chloro functionality facilitates nucleophilic substitution and elimination reactions, while the gem-dimethyl substitution enhances bench stability and simplifies purification. This compound functions effectively in coupling protocols and as a precursor to bioactive heterocycles, offering predictable reactivity in standard laboratory workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: