2-Bromo-5-chloropyrazolo[1,5-a]pyrimidine

Name: 2-Bromo-5-chloropyrazolo[1,5-a]pyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1780378-34-8
Cat. No. CS-0137916
Purity≥96%
MDL No.MFCD20258252

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-5-chloropyrazolo[1,5-a]pyrimidine|CS-0137916

Structure of 1780378-34-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Bromo-5-chloropyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with complementary halogen substituents enabling direct functionalization in cross-coupling reactions. The electron-deficient pyrazolopyrimidine scaffold supports efficient derivatization under palladium catalysis, delivering complex molecular architectures for medicinal chemistry and materials science applications.

Application

2-Bromo-5-chloropyrazolo[1,5-a]pyrimidine serves as a versatile building block for constructing substituted heterocycles in medicinal chemistry and agrochemical research. Its dual halogenation enables efficient Pd-catalyzed cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig aminations, with excellent functional group tolerance. The molecule exhibits good bench stability and facilitates rapid diversification of pyrazolo[1,5-a]pyrimidine scaffolds under standard reaction conditions.

General Information

CAS No. 1780378-34-8
Cat. No. CS-0137916
Purity ≥96%
MDL No. MFCD20258252
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃BrClN₃
Molecular Weight None
Synonym(s) None
SMILES ClC1=NC2=CC(Br)=NN2C=C1

Computational Chemistry Data

TPSA 30.19
LogP 2.1452
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

1780378-34-8 sigma1780378-34-8 manufacturer1780378-34-8 price1780378-34-8 structure1780378-34-8 SDSbuy 1780378-34-81780378-34-8 supplier1780378-34-8 uses1780378-34-8 molecular weightprice of 1780378-34-81780378-34-8 chemical name formula of 1780378-34-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-5-chloropyrazolo[1,5-a]pyrimidine

CAS No. 1780378-34-8

Recommended Products