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Structure of 1203705-58-1
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2-Bromo-7-chloropyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with complementary halogen substituents enabling direct functionalization in cross-coupling and cyclization reactions. The electron-deficient pyrimidine ring facilitates nucleophilic substitution, while the bromo and chloro groups provide orthogonal reactivity for sequential derivatization. This scaffold delivers high structural rigidity and enhanced metabolic stability, making it ideal for medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents.
2-Bromo-7-chloropyrazolo[1,5-a]pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through palladium-catalyzed cross-coupling reactions. Its dual halogenation pattern supports sequential functionalization, while the pyrazolo[1,5-a]pyrimidine core exhibits favorable stability and compatibility with diverse reaction conditions. The compound functions effectively in Suzuki, Stille, and Buchwald–Hartwig transformations, facilitating rapid access to complex molecular architectures relevant to drug discovery programs.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: