1,2,3,4-Tetrahydroquinaldine

Name: 1,2,3,4-Tetrahydroquinaldine
Brand: ChemScene
Availability: InStock
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CAS No. 1780-19-4
Cat. No. CS-W019554
Purity≥98%
MDL No.MFCD00023886

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1780-19-4

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Description

1,2,3,4-Tetrahydroquinaldine features a saturated quinoline core with enhanced solubility and reduced aromaticity, enabling efficient integration into catalytic systems. This bench-stable heterocycle serves as a key scaffold in medicinal chemistry, where its nitrogen-rich framework supports hydrogen bonding and metal coordination.

Application

1,2,3,4-Tetrahydroquinaldine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through standard functionalization protocols. Its saturated ring system offers enhanced stability and solubility compared to aromatic analogs, facilitating purification and handling. The molecule functions effectively as a nitrogen-containing synthon in transition-metal-catalyzed couplings and reductive amination reactions, supporting the construction of complex alkaloid frameworks and drug-like intermediates with predictable reactivity.

General Information

CAS No. 1780-19-4
Cat. No. CS-W019554
Purity ≥98%
MDL No. MFCD00023886
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₃N
Molecular Weight None
Synonym(s) Quinoline, 1,2,3,4-tetrahydro-2-methyl- (9CI)
SMILES CC1CCC2=CC=CC=C2N1

Computational Chemistry Data

TPSA 12.03
LogP 2.4332
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Key Words

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1,2,3,4-Tetrahydroquinaldine

CAS No. 1780-19-4

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