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CS-W001157 4
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Quinolin-2-ylmethanol

  • CAS No. 1780-17-2

  • Cat. No. CS-0044957
  • Purity≥98%
  • MDL No.MFCD00086626

*For research and further manufacturing use only, not for direct human use.

Quinolin-2-ylmethanol|CS-0044957

Structure of 1780-17-2

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General Information

  • CAS No. 1780-17-2
  • Cat. No. CS-0044957
  • Purity ≥98%
  • MDL No. MFCD00086626
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO
  • Molecular Weight 159.18
  • Synonym(s) 2-quinolylmethanol
  • SMILES OCC1=NC2=CC=CC=C2C=C1

Description

Quinolin-2-ylmethanol features a rigid quinoline scaffold with a reactive benzylic alcohol group, enabling direct functionalization in synthetic transformations. This bench-stable, moisture-tolerant heterocycle integrates readily into pharmaceutical intermediates and ligand architectures, offering predictable reactivity under standard conditions.

Application

Quinolin-2-ylmethanol serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through oxidation, coupling, and functionalization reactions. Its bench-stable nature and compatibility with common reaction conditions facilitate straightforward incorporation into target molecules. The alcohol functionality provides a reliable handle for derivatization, including ether formation and substitution reactions, making it a practical choice for synthetic route development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.7271
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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