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CS-W001157 4
Total: USD 88.00

5-Phenylpentan-1-amine

  • CAS No. 17734-21-3

  • Cat. No. CS-0096226
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Phenylpentan-1-amine|CS-0096226

Structure of 17734-21-3

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General Information

  • CAS No. 17734-21-3
  • Cat. No. CS-0096226
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇N
  • Molecular Weight 163.26
  • Synonym(s) Benzenepentanamine
  • SMILES NCCCCCC1=CC=CC=C1

Description

5-Phenylpentan-1-amine features a linear aliphatic chain terminating in a primary amine group, flanked by a phenyl ring at the γ-position. This structure confers enhanced solubility and stability compared to simpler aromatic amines, enabling efficient integration into peptide conjugation and medicinal chemistry scaffolds under standard conditions.

Application

5-Phenylpentan-1-amine serves as a versatile benzyl-containing aliphatic amine scaffold, enabling efficient access to functionalized intermediates in medicinal chemistry. Its primary amine functionality facilitates straightforward derivatization, while the pendant phenyl group provides structural rigidity and hydrophobic character useful in target-oriented synthesis. The compound exhibits good bench stability and compatibility with standard coupling and protection protocols, making it a practical building block for diverse molecular architectures.

Synthesis

  • Route1
    • null|null
      53429-14-4
    • ~96%
    • In-stock
      5-Phenylpentan-1-amine|CS-0096226
      17734-21-3

    References

    • Buschauer, A; Friese-Kimmel A; Baumann, G; Schunack, W European Journal of Medicinal Chemistry, 1992 , vol. 27, # 4 p. 321 - 330
  • Route2
    • null|null
      127611-46-5
    • ~84%
    • In-stock
      5-Phenylpentan-1-amine|CS-0096226
      17734-21-3

    References

    • Chhen, A.; Vaultier, M.; Carrie, R. Tetrahedron Letters, 1989 , vol. 30, # 37 p. 4953 - 4956
  • Route3

    References

    • Sun, Weilin; Pelletier, Jeffrey C. Tetrahedron Letters, 2007 , vol. 48, # 44 p. 7745 - 7746

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.3581
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   5

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