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Structure of 176967-80-9
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5-Bromo-8-nitroquinoline delivers a potent electron-deficient heterocyclic scaffold, combining a bromine substituent at the 5-position with a nitro group at the 8-position. This configuration enables direct functionalization in cross-coupling reactions and enhances reactivity in metal-catalyzed transformations. The molecule exhibits high stability under standard conditions and serves as a key building block for advanced pharmaceutical intermediates and materials chemistry applications.
5-Bromo-8-nitroquinoline serves as a versatile building block in medicinal chemistry and catalytic cross-coupling reactions. The bromo group enables palladium-catalyzed transformations such as Suzuki, Stille, and Negishi couplings, while the nitro functionality offers opportunities for selective reduction and further derivatization. Its stability under standard reaction conditions and compatibility with diverse functional groups make it a practical scaffold for constructing complex heterocyclic architectures in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: