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20-Methoxy-20-oxoicosanoic acid

  • CAS No. 1767-98-2

  • Cat. No. CS-0526925
  • Purity≥98%
  • MDL No.MFCD32196848

*For research and further manufacturing use only, not for direct human use.

20-Methoxy-20-oxoicosanoic acid|CS-0526925

Structure of 1767-98-2

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General Information

  • CAS No. 1767-98-2
  • Cat. No. CS-0526925
  • Purity ≥98%
  • MDL No. MFCD32196848
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₄₀O₄
  • Molecular Weight 356.55
  • Synonym(s) None
  • SMILES O=C(O)CCCCCCCCCCCCCCCCCCC(=O)OC

Description

20-Methoxy-20-oxoicosanoic acid features a terminal aldehyde group flanked by a methoxy and carbonyl functionality, enabling direct conjugation or derivatization in bioconjugation workflows. This extended hydrophobic chain enhances membrane permeability and metabolic stability, making it suitable for lipid-based delivery systems and probe synthesis.

Application

20-Methoxy-20-oxoicosanoic acid serves as a versatile β-keto ester surrogate in synthetic organic chemistry, enabling efficient construction of cyclic ketones and heterocyclic scaffolds via intramolecular aldol or Claisen-type cyclizations. Its methoxy carbonyl group enhances functional group tolerance and facilitates mild deprotection under acidic conditions. The compound exhibits excellent bench stability and is compatible with standard purification techniques, making it a practical building block for complex molecule synthesis in medicinal and process chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   6.2658
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   19

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