4,6-Dichlorobenzofuran

Name: 4,6-Dichlorobenzofuran
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 175203-95-9
Cat. No. CS-0163327
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 175203-95-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 175203-95-9
Cat. No. CS-0163327
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₄Cl₂O
Molecular Weight 187.02
Synonym(s) 4,6-DICHLORO-1-BENZOFURAN
SMILES ClC1=CC(Cl)=C2C=COC2=C1

Description

4,6-Dichlorobenzofuran is a halogenated heterocyclic compound featuring two chlorine substituents at the 4- and 6-positions of the benzofuran core. This configuration imparts enhanced electron deficiency and metabolic stability, making it a valuable scaffold in medicinal chemistry for probing bioactive molecular interactions.

Application

4,6-Dichlorobenzofuran serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the 2- and 5-positions via palladium-catalyzed cross-coupling reactions. Its electron-deficient aromatic core enhances reactivity in Suzuki-Miyaura and Stille couplings, while the fused heterocyclic framework provides structural rigidity and metabolic stability. Bench-stable and readily purified by column chromatography, it functions as a key scaffold for synthesizing bioactive molecules and conjugated polymers.

Synthesis

Route1
- 1391575-68-0
- ~67%
- In-stock
  
  175203-95-9
References
- Chernyak, Natalia; Buchwald, Stephen L. Journal of the American Chemical Society, 2012 , vol. 134, # 43 p. 18147 - 18147,1
Route2
- In-stock
  
  697-86-9
- ~%
- In-stock
  
  175203-95-9
References
- Chernyak, Natalia; Buchwald, Stephen L. Journal of the American Chemical Society, 2012 , vol. 134, # 43 p. 18147 - 18147,1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 13.14
LogP 3.7396
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Benzofuran compounds

Key Words

4,6-Dichlorobenzofuran sigma4,6-Dichlorobenzofuran manufacturer4,6-Dichlorobenzofuran price4,6-Dichlorobenzofuran structure4,6-Dichlorobenzofuran SDSbuy 4,6-Dichlorobenzofuran4,6-Dichlorobenzofuran supplier4,6-Dichlorobenzofuran uses4,6-Dichlorobenzofuran molecular weightprice of 4,6-Dichlorobenzofuran4,6-Dichlorobenzofuran chemical name formula of 4,6-Dichlorobenzofuran

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4,6-Dichlorobenzofuran

CAS No. 175203-95-9

Recommended Products