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CS-W001157 4
Total: USD 88.00

3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-amine

  • CAS No. 175136-34-2

  • Cat. No. CS-0063824
  • Purity≥97%
  • MDL No.MFCD00218806

*For research and further manufacturing use only, not for direct human use.

3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-amine|CS-0063824

Structure of 175136-34-2

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General Information

  • CAS No. 175136-34-2
  • Cat. No. CS-0063824
  • Purity ≥97%
  • MDL No. MFCD00218806
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) BUTTPARK 121\15-34
  • SMILES NC1=CC=C(OCCCO2)C2=C1

Description

(S)-2-amino-4-(2-(pyridin-2-yl)disulfanyl)butanoic acid is a small molecule reagent with a 2-thiopyridine linked to a short amino acid. SPDP is a thiol-specific labeling reagent, commonly used in reversibly binding cysteine residues on proteins. The disulfide bond it forms with the cysteine is selectively cleaved in the reducing environment of the cell cytoplasm.

Synthesis

  • Route1
    • 7-Nitro-3,4-dihydro-2H-benzo[b][1,4]dioxepine|CS-0466434
      78288-94-5
    • ~98%
    • In-stock
      3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-amine|CS-0063824
      175136-34-2

    References

    • Chilin, Adriana; Conconi, Maria Teresa; Marzaro, Giovanni; Guiotto, Adriano; Urbani, Luca; Tonus, Francesca; Parnigotto, Pierpaolo Journal of Medicinal Chemistry, 2010 , vol. 53, # 4 p. 1862 - 1866

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.4301
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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