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CS-W001157 4
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(4S)-Methyl-[1,3,2]dioxathiolane 2,2-dioxide

  • CAS No. 174953-30-1

  • Cat. No. CS-0155182
  • Purity≥95%
  • MDL No.MFCD26131320

*For research and further manufacturing use only, not for direct human use.

(4S)-Methyl-[1,3,2]dioxathiolane 2,2-dioxide|CS-0155182

Structure of 174953-30-1

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General Information

  • CAS No. 174953-30-1
  • Cat. No. CS-0155182
  • Purity ≥95%
  • MDL No. MFCD26131320
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆O₄S
  • Molecular Weight 138.14
  • Synonym(s) 1,3,2-Dioxathiolane, 4-methyl-, 2,2- dioxide, (4S)-
  • SMILES C1OS(O[C@H]1C)(=O)=O

Description

(4S)-Methyl-[1,3,2]dioxathiolane 2,2-dioxide is a chiral sulfone-containing heterocycle featuring a stable dioxathiolane core with defined stereochemistry at the 4-position. This bench-stable, moisture-tolerant scaffold serves as a key building block in asymmetric synthesis, enabling precise incorporation of sulfur-based functional groups into complex molecular architectures.

Application

(4S)-Methyl-[1,3,2]dioxathiolane 2,2-dioxide serves as a stable, bench-ready chiral synthon for the construction of sulfonamide-containing heterocycles and bioactive scaffolds. Its rigid bicyclic structure enables stereoselective transformations, while the sulfonyl group exhibits excellent functional group tolerance in coupling and derivatization reactions. The compound facilitates efficient access to medicinally relevant motifs through predictable reactivity patterns, making it a practical building block in synthetic medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   -0.3335
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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