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CS-W001157 4
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2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid

  • CAS No. 174879-28-8

  • Cat. No. CS-0152596
  • Purity≥97%
  • MDL No.MFCD00270362

*For research and further manufacturing use only, not for direct human use.

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid|CS-0152596

Structure of 174879-28-8

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General Information

  • CAS No. 174879-28-8
  • Cat. No. CS-0152596
  • Purity ≥97%
  • MDL No. MFCD00270362
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₉NO₄
  • Molecular Weight 325.36
  • Synonym(s) FMOC-DL-2-AMINOBUTYRIC ACID
  • SMILES CCC(NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C(O)=O

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a robust C-terminal carbamate group, enabling efficient coupling in solid-phase peptide synthesis. The fluoren-9-ylmethoxy carbonyl (Fmoc) moiety provides excellent orthogonal protection and facilitates mild deprotection under basic conditions. This bench-stable compound integrates seamlessly into complex peptide sequences with high fidelity.

Application

2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid serves as a robust amino acid derivative for peptide synthesis, offering excellent solubility and stability under standard coupling conditions. The Fmoc group enables efficient, orthogonal protection of the amine, facilitating selective deprotection during iterative chain elongation. Its well-documented compatibility with common coupling reagents and ease of purification make it a practical choice for solid-phase and solution-phase peptide assembly workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.3883
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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