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CS-W001157 4
Total: USD 88.00

(4-Bromo-2,6-dimethylphenyl)hydrazine hydrochloride

  • CAS No. 174826-34-7

  • Cat. No. CS-0159093
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-Bromo-2,6-dimethylphenyl)hydrazine hydrochloride|CS-0159093

Structure of 174826-34-7

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General Information

  • CAS No. 174826-34-7
  • Cat. No. CS-0159093
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂BrClN₂
  • Molecular Weight 251.55
  • Synonym(s) (4-bromo-2,6-dimethylphenyl)hydrazinehydrochloride
  • SMILES NNC1=C(C)C=C(Br)C=C1C.[H]Cl

Description

This hydrazine derivative features a brominated, dimethyl-substituted aromatic core that enhances electronic tuning and steric profile. The hydrochloride salt improves crystallinity and handling stability, enabling reliable use in transition metal-catalyzed couplings and heterocycle synthesis under standard conditions.

Application

(4-Bromo-2,6-dimethylphenyl)hydrazine hydrochloride serves as a versatile building block in the synthesis of heterocyclic scaffolds, particularly triazoles and imidazoles, via cycloaddition or condensation reactions. Its bromo and methyl substituents provide orthogonal reactivity and steric control, enabling efficient functionalization in medicinal chemistry applications. The hydrazine moiety offers high reactivity with carbonyl compounds and azodicarboxylates, while the hydrochloride salt ensures bench stability and ease of handling.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.77334
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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