Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Chloro-4-hydroxypyridine

  • CAS No. 17368-12-6

  • Cat. No. CS-D1163
  • Molecule weight129.54
  • Purity≥95%
  • MDL No.MFCD01646108

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4-hydroxypyridine|CS-D1163

Structure of 17368-12-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 17368-12-6
  • Cat. No. CS-D1163
  • Purity ≥95%
  • MDL No. MFCD01646108
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄ClNO
  • Molecular Weight 129.54
  • Synonym(s) 2-Chloro-4-pyridinol
  • SMILES OC1=CC(Cl)=NC=C1

Description

2-Chloro-4-hydroxypyridine features a strategically positioned hydroxyl group flanking a chloropyridine core, enabling direct functionalization in late-stage synthesis. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and serves as a key intermediate for bioactive molecule development under standard conditions.

Application

2-Chloro-4-hydroxypyridine serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the C2 position via nucleophilic substitution. The hydroxyl group provides a handle for derivatization, while the chlorine offers reliable reactivity in palladium-catalyzed cross-coupling reactions. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing heterocyclic scaffolds and pharmaceutical intermediates.

Synthesis

  • Route1

    References

    • SHOWA DENKO K.K. Patent: WO2009/11447 A2, 2009 ; Location in patent: Page/Page column 37-38 ;
  • Route2

    References

    • Kuduk, Scott D.; DiPardo, Robert M.; Bock, Mark G. Organic Letters, 2005 , vol. 7, # 4 p. 577 - 579
  • Route3

    References

    • Voisin, Anne Sophie; Bouillon, Alexandre; Lancelot, Jean-Charles; Rault, Sylvain Tetrahedron, 2005 , vol. 61, # 6 p. 1417 - 1421

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.4406
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Chloro-4-hydroxypyridine sigma2-Chloro-4-hydroxypyridine manufacturer2-Chloro-4-hydroxypyridine price2-Chloro-4-hydroxypyridine structure2-Chloro-4-hydroxypyridine SDSbuy 2-Chloro-4-hydroxypyridine2-Chloro-4-hydroxypyridine supplier2-Chloro-4-hydroxypyridine uses2-Chloro-4-hydroxypyridine molecular weightprice of 2-Chloro-4-hydroxypyridine2-Chloro-4-hydroxypyridine chemical name formula of 2-Chloro-4-hydroxypyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label