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CS-W001157 4
Total: USD 88.00

6-Ethynylpyridin-2-amine

  • CAS No. 173314-98-2

  • Cat. No. CS-0309307
  • Molecule weight118.14
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Ethynylpyridin-2-amine|CS-0309307

Structure of 173314-98-2

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General Information

  • CAS No. 173314-98-2
  • Cat. No. CS-0309307
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂
  • Molecular Weight 118.14
  • Synonym(s) 6-Ethynyl-2-pyridinaMine
  • SMILES C#CC1=NC(=CC=C1)N

Description

6-Ethynylpyridin-2-amine delivers a reactive alkyne handle ortho to a primary amine, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and materials assembly. This bench-stable, moisture-tolerant building block integrates seamlessly into functional molecular architectures.

Application

6-Ethynylpyridin-2-amine serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted heterocycles via copper-catalyzed coupling reactions. Its orthogonal functionality—combining a terminal alkyne and a primary amine—facilitates modular assembly of complex scaffolds, including triazoles and conjugated systems. The compound exhibits excellent bench stability and compatibility with standard purification protocols, making it ideal for medicinal chemistry campaigns and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.6451
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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