Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-one

  • CAS No. 173252-76-1

  • Cat. No. CS-0137756
  • Molecule weight216.16
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-one|CS-0137756

Structure of 173252-76-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 173252-76-1
  • Cat. No. CS-0137756
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇F₃O₂
  • Molecular Weight 216.16
  • Synonym(s) 5-(trifluoromethoxy)-2,3-dihydroinden-1-one
  • SMILES O=C1CCC2=C1C=CC(OC(F)(F)F)=C2

Description

5-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-one features a trifluoromethoxy group at the 5-position of a partially saturated indenone scaffold. This electron-deficient ketone integrates readily into synthetic sequences requiring polar, moisture-tolerant building blocks. The fused ring system provides rigidity and enhanced stability under standard bench conditions.

Application

5-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-one serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the reactive ketone facilitates nucleophilic addition, reductive amination, and enolate chemistry. The dihydroindene core offers structural rigidity and compatibility with standard coupling and functionalization protocols, making it valuable for lead optimization in drug discovery.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.7141
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 173252-76-1 sigma173252-76-1 manufacturer173252-76-1 price173252-76-1 structure173252-76-1 SDSbuy 173252-76-1173252-76-1 supplier173252-76-1 uses173252-76-1 molecular weightprice of 173252-76-1173252-76-1 chemical name formula of 173252-76-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label