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Structure of 81333-06-4
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6-Chloropyrimidine-4-carboxamide is a bench-stable heterocyclic building block featuring a chlorinated pyrimidine core paired with a carboxamide functional group. This combination enables direct incorporation into pharmaceutical intermediates, facilitating coupling reactions under mild conditions. The electron-deficient ring enhances reactivity in nucleophilic substitution processes, while the amide moiety provides solubility and hydrogen-bonding capacity for downstream applications in medicinal chemistry and agrochemical development.
6-Chloropyrimidine-4-carboxamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its chlorine at C6 facilitates nucleophilic substitution, while the carboxamide group offers hydrogen-bonding capacity and synthetic handle for derivatization. The compound exhibits good bench stability and is compatible with standard coupling reactions, making it well-suited for parallel synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: