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Structure of 172846-36-5
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tert-Butyl (6-iodohexyl)carbamate is a bench-stable, moisture-tolerant carbamate protecting group that integrates a reactive iodide handle at the distal end of a six-carbon chain. This structure enables efficient coupling in late-stage functionalization and diversification workflows. The pendant iodine atom facilitates transition metal-catalyzed transformations such as cross-couplings, enabling rapid access to complex molecular architectures.
tert-Butyl (6-iodohexyl)carbamate serves as a versatile bifunctional building block for C–C and C–heteroatom coupling reactions. The iodide moiety enables reliable Stille, Suzuki, and Negishi cross-couplings, while the tert-butoxycarbonyl (Boc) group provides orthogonal protection for primary amines. Its bench-stable nature and ease of purification facilitate integration into multi-step syntheses, including peptidomimetics and functionalized alkyl chains in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: