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tert-Butyl (5-iodopentyl)carbamate

  • CAS No. 262278-05-7

  • Cat. No. CS-0312164
  • Purity≥95%
  • MDL No.MFCD18384789

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (5-iodopentyl)carbamate|CS-0312164

Structure of 262278-05-7

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General Information

  • CAS No. 262278-05-7
  • Cat. No. CS-0312164
  • Purity ≥95%
  • MDL No. MFCD18384789
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀INO₂
  • Molecular Weight 313.18
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCCCCI

Description

tert-Butyl (5-iodopentyl)carbamate delivers a reactive iodide handle at the terminus of a flexible pentyl chain, enabling efficient coupling in palladium-catalyzed transformations. This bench-stable carbamate protects primary amines while its iodide group facilitates conjugation under mild conditions.

Application

tert-Butyl (5-iodopentyl)carbamate serves as a versatile, bench-stable building block for the synthesis of functionalized amines and heterocyclic scaffolds. The iodide group enables efficient palladium-catalyzed cross-coupling reactions, while the tert-butyl carbamate (Boc) moiety provides reliable protection of primary amines. This combination facilitates orthogonal functionalization in multi-step syntheses, offering high compatibility with standard reaction conditions and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H315-H318-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   3.1164
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   5

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