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Structure of 17228-74-9
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2,6-Dichloro-4-hydroxypyridine features a pyridine core functionalized with two chlorine substituents at the 2 and 6 positions and a hydroxyl group at the 4 position. This arrangement imparts enhanced electrophilicity at the C4 position, enabling efficient coupling reactions in heterocyclic synthesis. The compound exhibits bench-stable handling characteristics and serves as a key intermediate for pharmaceutical and agrochemical derivatives requiring regioselective functionalization.
2,6-Dichloro-4-hydroxypyridine serves as a versatile building block for the synthesis of pyridine-based pharmaceutical intermediates and agrochemicals. The hydroxyl group enables direct derivatization via etherification or esterification, while the dichloro substituents facilitate nucleophilic aromatic substitution under mild conditions, allowing efficient access to diverse substituted pyridines. Its bench-stable nature and compatibility with common reaction protocols make it a practical choice for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: