Spiro[2.2]pentane-1-carboxylic acid

Name: Spiro[2.2]pentane-1-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 17202-64-1
Cat. No. CS-0048700
Molecule weight112.13
Purity≥97%
MDL No.MFCD04038995

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Spiro[2.2]pentane-1-carboxylic acid|CS-0048700

Structure of 17202-64-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 17202-64-1
Cat. No. CS-0048700
Purity ≥97%
MDL No. MFCD04038995
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₈O₂
Molecular Weight 112.13
Synonym(s) Spiro[2.2]pentane-5-carboxylic acid
SMILES OC(=O)C1CC11CC1

Description

Spiro[2.2]pentane-1-carboxylic acid delivers a rigid, three-dimensional scaffold with enhanced metabolic stability and improved solubility profiles. The spirocyclic core resists conformational flexibility, while the carboxylic acid group enables direct conjugation or derivatization under standard conditions. This structure facilitates efficient incorporation into bioactive molecules requiring steric shielding and controlled polarity.

Application

Spiro[2.2]pentane-1-carboxylic acid serves as a rigid, bicyclic building block for medicinal chemistry and materials science, offering enhanced metabolic stability and conformational constraint. Its carboxylic acid functionality enables direct derivatization via standard coupling reactions, while the spirocyclic core imparts excellent bench stability and orthogonal reactivity in multi-step syntheses.

Synthesis

Route1
- 75-11-6
- 18941-94-1
- ~%
- In-stock
  
  17202-64-1
References
- Journal of Organic Chemistry, , vol. 33, p. 3828 - 3838

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.3
LogP 0.8711
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Building Blocks Skeleton Spirol Rings compounds

Key Words

Spiro[2.2]pentane-1-carboxylic acid sigmaSpiro[2.2]pentane-1-carboxylic acid manufacturerSpiro[2.2]pentane-1-carboxylic acid priceSpiro[2.2]pentane-1-carboxylic acid structureSpiro[2.2]pentane-1-carboxylic acid SDSbuy Spiro[2.2]pentane-1-carboxylic acidSpiro[2.2]pentane-1-carboxylic acid supplierSpiro[2.2]pentane-1-carboxylic acid usesSpiro[2.2]pentane-1-carboxylic acid molecular weightprice of Spiro[2.2]pentane-1-carboxylic acidSpiro[2.2]pentane-1-carboxylic acid chemical name formula of Spiro[2.2]pentane-1-carboxylic acid

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Spiro[2.2]pentane-1-carboxylic acid

CAS No. 17202-64-1

Recommended Products