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CS-W001157 4
Total: USD 88.00

Cl-PEG2-acid

  • CAS No. 170304-76-4

  • Cat. No. CS-0046441
  • Purity≥97%
  • MDL No.MFCD20623441

*For research and further manufacturing use only, not for direct human use.

Cl-PEG2-acid|CS-0046441

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General Information

  • CAS No. 170304-76-4
  • Cat. No. CS-0046441
  • Purity ≥97%
  • MDL No. MFCD20623441
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁ClO₄
  • Molecular Weight 182.60
  • Synonym(s) None
  • SMILES O=C(O)COCCOCCCl

Description

Cl-PEG2-acid features a chloro-functionalized terminus on a short-chain PEG spacer, enabling selective conjugation with nucleophilic amines. This bifunctional architecture combines the solubility and stability of PEGylation with reactive halogen chemistry, streamlining the attachment of peptides, proteins, or small molecules in bioconjugation workflows under mild conditions.

Application

Cl-PEG2-acid serves as a versatile bifunctional linker for conjugation and polymer synthesis, combining the robustness of a chloroalkyl activation site with a terminal carboxylic acid. It enables efficient coupling to amine-containing biomolecules or resins under mild conditions, while its PEG2 spacer enhances solubility and reduces non-specific binding. Ideal for drug delivery systems and diagnostic probes, it offers reliable stability, straightforward purification, and compatibility with standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   0.343
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   7

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