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Structure of 1698028-11-3
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7-Bromo-2,4,6-trichloro-8-fluoroquinazoline features a highly electron-deficient quinazoline core with strategically positioned halogens enabling diverse cross-coupling transformations. This bench-stable scaffold integrates readily into pharmaceutical intermediates and functional materials, offering predictable reactivity in palladium-catalyzed processes under standard conditions.
7-Bromo-2,4,6-trichloro-8-fluoroquinazoline serves as a versatile building block for the synthesis of substituted quinazolines via palladium-catalyzed cross-coupling reactions. The strategically positioned halogen atoms enable sequential functionalization at C7 (bromine) and C8 (fluorine), while the electron-deficient core enhances reactivity in nucleophilic substitution processes. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for medicinal chemistry campaigns requiring rapid diversification of quinazoline scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: