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CS-W001157 4
Total: USD 88.00

3-Fluoropyrrolidine hydrochloride

  • CAS No. 169750-17-8

  • Cat. No. CS-W005668
  • Purity≥95%
  • MDL No.MFCD04038329

*For research and further manufacturing use only, not for direct human use.

3-Fluoropyrrolidine hydrochloride|CS-W005668

Structure of 169750-17-8

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General Information

  • CAS No. 169750-17-8
  • Cat. No. CS-W005668
  • Purity ≥95%
  • MDL No. MFCD04038329
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClFN
  • Molecular Weight 125.57
  • Synonym(s) Pyrrolidine, 3-fluoro-, hydrochloride
  • SMILES FC1CNCC1.[H]Cl

Description

3-Fluoropyrrolidine hydrochloride is a bench-stable, moisture-tolerant heterocyclic building block featuring a fluorinated pyrrolidine core. This compound integrates readily into bioactive molecule synthesis, where the fluorine atom enhances metabolic stability and modulates electronic properties. Its crystalline form ensures ease of handling and reproducible dosing in medicinal chemistry workflows.

Application

3-Fluoropyrrolidine hydrochloride serves as a valuable fluorinated building block in medicinal chemistry, enabling site-specific introduction of fluorine into bioactive molecules. Its stability, solubility, and compatibility with standard amine coupling protocols facilitate efficient incorporation into diverse scaffolds. Functions as a key intermediate in the synthesis of fluorinated heterocycles and peptide-like compounds, offering enhanced metabolic stability and modulated lipophilicity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   0.7396
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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