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CS-W001157 4
Total: USD 88.00

(S)-3-(N-Boc-n-methylamino)pyrrolidine

  • CAS No. 169750-01-0

  • Cat. No. CS-W003552
  • Purity≥95%
  • MDL No.MFCD08703388

*For research and further manufacturing use only, not for direct human use.

(S)-3-(N-Boc-n-methylamino)pyrrolidine|CS-W003552

Structure of 169750-01-0

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General Information

  • CAS No. 169750-01-0
  • Cat. No. CS-W003552
  • Purity ≥95%
  • MDL No. MFCD08703388
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂O₂
  • Molecular Weight 200.28
  • Synonym(s) tert-butyl methyl[(3S)-pyrrolidin-3-yl]carbamate
  • SMILES O=C(N([C@@H]1CNCC1)C)OC(C)(C)C

Description

(S)-3-(N-Boc-N-methylamino)pyrrolidine is a chiral pyrrolidine derivative featuring a sterically hindered, bench-stable Boc-protected amine and a methylated nitrogen. This configuration enables direct incorporation into complex peptide scaffolds and bioactive molecules without racemization, streamlining synthesis in medicinal chemistry workflows.

Application

(S)-3-(N-Boc-N-methylamino)pyrrolidine serves as a versatile chiral building block for the synthesis of bioactive nitrogen-containing heterocycles. Its Boc-protected amine and methylated nitrogen enable orthogonal functionalization, while the pyrrolidine scaffold provides a rigid, conformationally defined framework suitable for medicinal chemistry applications. The compound exhibits excellent bench stability, facilitates straightforward purification, and participates reliably in standard coupling and reductive amination protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.2152
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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